Welcome to the Microbiomechanics Laboratory
Strain Gauge Arrays for Bones
The Microbiomechanics Laboratory aims at studying biological systems at the micro- and nano-scales with mechanically-derived modalities. In traditional biomechanics, the human body is viewed as an intricate collection of interacting mechanical structures and systems that exhibit both static and dynamic mechanical behaviors. These studies are usually confined to the level of the entire organisms, physiological subsystems, or individual organs. The rapid advances in Micro-Electro-Mechanical Systems (MEMS) technologies offer a set of powerful tools that allows studying biomechanics at the micro scale. This will shed lights on the finer details of biomechanics, and may uncover fundamental knowledge of the origin of mechanical behaviors in living organisms.
We develop devices and platforms that enable both in-vitro and in-vivo studies of the mechanical aspects in physiological activities involving cells, tissues, and organs. They would be suitable for interfacing and interrogating the mechanical phenomena of interest within the targeted physiological activities at the length-scales that are beyond the reach of traditional biomedical instrumentations. Our vision is that these devices and platforms will enable new research efforts to understand the significance of biomechanics at the most basic unit of life -the cell. We also envision enabling clinically-relevant applications that require accurate real-time data on the stress strain distributions in the organs or physiological systems for investigation and diagnosis of the mechanical implications of health and diseases within the organs. We further envision leveraging the understanding in physiological phenomena researched with these tools to develop prosthetic devices to restore both sensory and motor functions that are mechanical in nature within the body.
January 9, 2015
Congratulations! Tasnim Ahmed (3rd time), Lydia Ameri (4th time), Claudia Cetrola (3rd time), Anthony Han (3rd time), Emily Kha (3rd time), Bita Kianian (1st time), Nick Look (1st time), Ci Ren (1st time), Cyril Soliman (1st time) and Yijiao Wang (4th time) were appointed the Undergraduate Research Opportunities Program (UROP) Fellows for the 2014-2015 academic year during the Fall Call for Proposals.
June 30, 2014
Tasnim Ahmed, Lydia Ameri, Claudia Cetrola, Gary Chang, Anthony Han, Emily Kha, and Yijiao Wang were appointed the Undergraduate Research Opportunities Program (UROP) Fellows for the 2014-2015 academic year during the Spring Call for Proposals.
May 28, 2014
Claudia Cetrola was appointed the Edwards Lifesciences Summer Undergraduate Research Program (E-SURP) Fellow for Summer 2014.
January 20, 2014
Tasnim Ahmed, Lydia Ameri, Gary Chang, Anthony Han, Emily Kha, Michael Lum, Indrani Mikkilineni, Kishan Patel, Aswini Ponnaluri, and Yijiao Wang were appointed the Undergraduate Research Opportunities Program (UROP) Fellows for the 2013-2014 academic year.
January 14, 2014
Prof. William C. Tang and his ex-student, Dr. Yu-Hsiang Hsu, were awarded the U.S. Patent on their malaria detection invention:
W. C. Tang and Y.-H. Hsu, “Microfluidic devices and methods for malaria detection,” U.S. Patent #8,628,972, January 14, 2014.
January 15, 2013
Lydia Ameri, Gary Chang, Hanna Chang, Michael Lum, Indrani Mikkilineni, Shravya Nagurla, Andrea Navarro, Kishan Patel, Aswini Ponnaluri, Abdullah Siddiqui, Tracey Tien, and Yijiao Wang were appointed the Undergraduate Research Opportunities Program (UROP) Fellows for the 2012-2013 academic year.
November 5, 2012
Prof. William C. Tang was awarded $1.65m Phase II of the Pricision Rate-Integrating Micro Gyroscope program from DARPA to continue his collaborative research with the
August 2, 2011
Prof. William C. Tang and his students were awarded the U.S. Patent on their neural probe invention:
W. C. Tang, J. Wu, and R. Hainley, “High density micromachined electrode arrays useable for auditory nerve implants and related methods,” U.S. Patent #7,991,475, August 2, 2011.
July 20, 2011
Prof. William C. Tang in collaboration with Dr. Alex Trusov (Mechanical and Aerospace Engineering) and Dr. Karl Yee (Jet Propulsion Laboratory) was awarded a grant of over $2.7m by the Defense Advanced Research Projects Agency (DARPA). Prof. Tang as the Principal Investigator will lead this three-year effort to pursue research on Precision Rate-Integrating Micro Gyroscope.
June 24, 2011
Michael Lum, Shravya Nagurla, Andrea Navarro, and Tracey Tien were appointed the Undergraduate Research Opportunities Program (UROP) Fellows for the 2011-2012 academic year.
May 24, 2011
Both Andrea Navarro and Tracey Tien were appointed the Edwards Lifesciences Summer Undergraduate Research Program (E-SURP) Fellows for their poroposal on microplatforms for studying the biomechanics of cardiomyocytes.
January 1, 2011
Prof. William C. Tang was re-appointed as the Associate Dean for Research for the Henry Samueli School of Engineering. At the same time, he has stepped down from the position of Associate Chair for Undergraduate Education for the Biomedical Engineering Department. Details of his Associate Dean appointment can be found at:
September 21, 2010
Prof. William C. Tang was awarded the 2010 Fariborz Maseeh Outstanding Faculty Teaching Award during the Annual Dinner and Awards Banquet of the Henry Samueli School of Engineering.
July 1, 2010
Prof. William C. Tang has completed his duties both as Associate Dean for Research for the Henry Samueli School of Engineering and Acting Chair for the Department of Biomedical Engineering. He now takes on the responsibilities of the Associate Chair for Undergraduate Education for the Department.
July 1, 2009
Prof. William C. Tang has assumed the additional role of acting chair for the Department of Biomedical Engineering
March 5, 2008
Prof. William C. Tang has been appointed as the first Associate Dean for Research for the Henry Samueli School of Engineering. His appointment will begin at the start of spring quarter, 2008. Details can be found at:
September 8, 2006
The Orange County Chapter of the IEEE Engineering in Medicine and Biology is officially established. Dr. William C. Tang is the founding Chairman of the Chapter.
May 13, 2006
Dr. William C. Tang was given the 2006 Chancellor's Award for Excellence in Undergraduate Research "to recognize the meritorious contributions in support of undergraduate research."
Dr. William C. Tang was elected Fellow of the American Institute for Medical and Biological Engineering for "Significant contribution in the field of BioMEMS and Nano-scale technologies"